oalib

OALib Journal期刊

ISSN: 2333-9721

费用:99美元

投稿

时间不限

( 2673 )

( 2672 )

( 2024 )

( 2023 )

自定义范围…

匹配条件: “Chiara Peterle” ,找到相关结果约3246条。
列表显示的所有文章,均可免费获取
第1页/共3246条
每页显示
DARPP-32 and t-DARPP isoform in non-small cell lung cancer (NSCLC): could they drive patients’ clinical management and be a therapeutic target?
Chiara Peterle,Francesco Gelsomino,Giuseppe Lamberti
- , 2018,
Abstract: Lung cancer remains the main cause of cancer-related death worldwide (1). In the last decade, the most significant improvements in non-small cell lung cancer (NSCLC) have been made through identification and exploiting of novel therapeutic targets. Among them, sensitizing EGFR mutations, ALK and ROS-1 gene rearrangements are the main targetable alterations that have deeply changed both clinical management and outcomes of these patients. Furthermore, the new antibody agents directed against programmed death 1 (PD-1) protein or its ligand (PD-L1) have recently opened the way to a new paradigm shift in the treatment strategies of different solid tumors, including lung cancer
Tc99m-HMPAO white blood cell scintigraphy: added value of SPECT/CT for infection diagnosis in cardiothoracic surgery
Napoleone Prandini,Stefano Panareo,Rosario Cultrera,Chiara Peterle
Chest Disease Reports , 2012, DOI: 10.4081/cdr.2012.e5
Abstract: We report a case of a woman who came to our attention because of fever and a sternal fistula draining purulent fluid. Four years before, she had undergone cardiothoracic surgery to place a patch because of a myocardial rupture. Under suspicion of a deep mediastinal infection, a Tc99m-HMPAO white blood cell (WBC) scintigraphy was performed. The use of planar imaging and single photon emission computed tomography (SPECT/CT) imaging allowed the identification of a sternal infection, which involved the anterior mediastinum up to pericardium and diaphgram. SPECT/CT led to a precise diagnosis of a thoracic infection, providing the location and extent of the disease. This turned out useful to improve therapeutic strategies.
Da política à literatura: o percurso de Ignazio Silone
Peterle, Patricia;
Alea : Estudos Neolatinos , 2009, DOI: 10.1590/S1517-106X2009000100009
Abstract: the first half of the xx century can be examined through political, historical and cultural events that influenced the whole generation of writers, artists and intellectuals. in this complex fabric are intertwined the binomials history and literature and literature and politics, in which can be inserted the trajectory of ignazio silone. his intellectual production reflects his insertion in the world and the experience of the experienced in life, which also bear the mark of totalitarian regimes, fascism, antifascism and by exile: marks of an existence that permeate and nourish silone's literary speech.
O caminho solitário e a intensa reflex o: Trabalhar cansa, de Pavese
Patricia Peterle
Alea : Estudos Neolatinos , 2009, DOI: 10.1590/s1517-106x2009000200017
Abstract:
O trabalho: a chave para a liberdade
Andreia Guerini,Patricia Peterle
Alea : Estudos Neolatinos , 2009, DOI: 10.1590/s1517-106x2009000100015
Abstract:
Família e ciclo vital: a fase de aquisi o
Juliana Peterle Ronchi,Luziane Zacché Avellar
Psicologia em Revista , 2011,
Abstract: Esta pesquisa objetivou descrever as características da fase deaquisi o, primeira fase do ciclo vital familiar, marcada pela uni odo casal e a convivência com os filhos pequenos. O estudo foirealizado com 50 famílias de classe média, na fase de aquisi o dociclo vital da família, da cidade de Vitória-ES. Os participantesresponderam ao questionário baseado na pesquisa Ciclo vital dafamília paulista, que se mostrou adequado para compreender adinamica e os valores das famílias da cidade de Vitória. Os dadoscoletados foram submetidos ao programa SPSS para Windows e,em seguida, realizamos análise qualitativa dos dados. Em Vitória,a família em fase de aquisi o se mostrou mais tradicional, comconflitos relacionados a assuntos de extradinamica familiar, comodinheiro e satisfa o profissional.
Time Competition. The New Strategic Frontier  [PDF]
Chiara Demartini, Piero Mella
iBusiness (IB) , 2011, DOI: 10.4236/ib.2011.32020
Abstract: The acceleration of change necessitates strategies to control time, considered not only as a variable that influences the temporal evolution of phenomena but as one that directly influences phenomena itself. This study tries to present the logic of time compression and time to market, as well as the main instruments for the formulation of time-based strategies, not only by observing how the value of time is perceived as a contraction of production and distribution lead times but also by considering the choice of the most opportune moment to start a business and introduce (or withdraw) a new product. Starting from a discussion of time-based competition managerial approaches, this study develops a theoretical framework showing different time-based methodologies (JIT, MRP, OPT, FMS, PERT, HSM) that help management to adopt time-based strategies. It also puts forward a taxonomy of time-based strategies as well as a logical strategic path to time value.
Reducing seismic risk by understanding its cultural roots: Inference from an Italian case history  [PDF]
Francesco Stoppa, Chiara Berti
Natural Science (NS) , 2013, DOI: 10.4236/ns.2013.58A1010
Abstract:

The paper discusses how to approach the problem of the social mitigation of seismic risk, in order to reduce damage and grief consequent to earthquakes. An alert protocol, intended as a working hypothesis, is proposed based on the experience gained from analysis of the behaviour and social response to the threat before and after the great disaster of the L’Aquila earthquake on 6th April 2009. Authors propose a protocol addressing four levels of increasing alert based on signs of earthquake preparation and social concerns. In this sense, it works as an intensity scale and does not strictly relate to earthquake size (magnitude) or seismic hazard. The proposed alert protocol provides sensible measures for reducing vulnerability, which is the only factor that can be more or less efficiently controlled, based on structural and behavioural adjustments. Factors indicating the difficult relationship between politicians, scientific community and citizens are considered: 1) a serious gap between researchers and citizens; 2) measures adopted by local administrators and the National Civil Protection Service not agreed by the population; 3) misunderstanding originated from a lack of clarity of communication about scientific terminology; and 4) the lack of an alert procedure protocol. In the current situation, all these problems are crucial and contribute to the unpreparedness to face a seismic event, and thus greatly increase the risk. The adoption and implementation of an alert procedure protocol requires a preliminary assessment of the context and should be adapted to the local sensibility and culture. The application of a protocol may reduce the contrasts between preventive measures and individual responsibilities, making mitigation measures more feasible and socially acceptable. In this paper, risk evaluation is not strictly related to probabilistic or deterministic predictions. In fact, this is a result of a project that comes from the general analysis of risk and is not intended to give an alternative hazard estimate method. This paper proposes an alert protocol addressing four levels of increasing alert based on signs of earthquake generating preparation and social concerns. Finally, there is a suggestion on how to gradually communicate the threat and get citizens involved in the risk mitigation process.

Mental health literacy and the anxiety disorders  [PDF]
Adrian Furnham, Chiara Lousley
Health (Health) , 2013, DOI: 10.4236/health.2013.53A071
Abstract:

Context: This study set out to investigate the mental health literacy (MHL) about eight anxiety disorders (ADs), using vignette methodology. Methods: In all 317 British Adult participants completed a questionnaire with vignettes describing eight anxiety disorders including OCD, PTSD, Agoraphobia, Specific Phobias, Social Phobia, Separation Anxiety Disorder, GAD and Panic Disorder. Recognition, beliefs about treatments and perceived life adjustment (happiness, success at work) of specific people with these disorders were assessed. Results: Literacy levels varied across anxiety disorders, with high recognition of OCD (64.67%), but very poor for panic disorder (1.26%), GAD (2.84%) and separation anxiety disorder (5.99%). There were few significant effects of vignette gender on literacy levels. MHL for most anxiety disorders was relatively low; particularly panic disorder, GAD and separation anxiety disorder. Social Phobics were judged as least happy and adjusted and agoraphobics least successful at work and would benefit most from psychological help. Conclusions: Overall recognition of the anxiety disorders was poor. Beliefs about adjustment and treatment varied widely as a function of each disorder. Implications of the research for education of the public and limitations of this research are considered.

Hospital Admissions and Mortality in Patients with Rheumatic Heart Disease in Brazil: An Analysis from 2008 to 2018  [PDF]
Mariana Silva Nunes, Gustavo Tedde-Filho, Jo?o Carlos Geber-Júnior, Willian Darwin Júnior, Viviane Uliane Peterle, Ana Paula Monteiro Gomides
Advances in Infectious Diseases (AID) , 2020, DOI: 10.4236/aid.2020.104015
Abstract: Introduction: The Rheumatic Fever (RF) is a systemic inflammatory disease, caused by Group A beta-hemolytic Streptococcus, predominating in children and adolescents. The clinical manifestations are varied and included in Jones Criteria for diagnosis. The cardiac manifestations are the most relevant, causing severe sequelae such as valvulitis. The RF is still a major public health problem in developing countries despite its primary prophylaxis being simple and effective if well applied. The overall objective of this study was to evaluate the number of hospital admissions and deaths in Brazil from 2008 to 2018. Methodology: Cross-sectional, descriptive, quantitative, documentary study with database provided by the Health Informatics Department of the Brazilian Ministry of Health (DATASUS). Results: In the studied period, a higher prevalence was observed among females (48,232 hospitalizations) and in the adult age group (59,270 hospitalizations and 3972 deaths). The total number of hospitalizations was 83,209 and the total number of deaths was 6572. The total mortality rate was 7.84. The region with the highest number of hospitalizations was the Southeast (22,863 hospitalizations). The total amount spent in hospitalizations was R$879,676,458.63, with an average value per hospitalization of R$ 10,496.21. The average length of stay was 12.7 days. Conclusion: Rheumatic heart disease is an important cause of hospitalizations in Brazil. Measures of early diagnosis and adequate treatment should be strongly stimulated.
第1页/共3246条
每页显示


Home
Copyright © 2008-2020 Open Access Library. All rights reserved.